Title : Curcumin metabolites contribute to the effect of curcumin on ameliorating insulin sensitivity in high-glucose-induced insulin-resistant HepG2 cells.

Pub. Date : 2020 Sep 15

PMID : 32464315






1 Functional Relationships(s)
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1 Similar to CUR, hexahydrocurcumin (HHC) and octahydrocurcumin (OHC) improved insulin sensitivity by strengthening the PI3K-AKT-GSK3B signal and suppressing the phosphorylation of ERK/JNK in HG-induced insulin-resistant HepG2 cells. Octahydrocurcumin mitogen-activated protein kinase 8 Homo sapiens