Title : Evaluating the Activity of Sodium Butyrate to Prevent Osteoporosis in Rats by Promoting Osteal GSK-3β/Nrf2 Signaling and Mitochondrial Function.

Pub. Date : 2020 Jun 17

PMID : 32459091






2 Functional Relationships(s)
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1 In particular, NaB promoted the activity of mitochondrial antioxidant enzymes and energy metabolism, preserved bone microstructure and calcium homeostasis, and activated bone metabolism, as shown by increased Nrf2/GSK-3beta signaling and the upregulation of PGC-1alpha and TFAM. nab NFE2 like bZIP transcription factor 2 Rattus norvegicus
2 In conclusion, NaB promoted the Nrf2/GSK-3beta signaling pathway and mitochondrial function, and is a potential new therapeutic strategy for obesity and osteoporosis. nab NFE2 like bZIP transcription factor 2 Rattus norvegicus