Title : NLRP3 inflammasome-dependent pyroptosis and apoptosis in hippocampus neurons mediates depressive-like behavior in diabetic mice.

Pub. Date : 2020 Aug 5

PMID : 32454054






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 It was found that STZ treatment induced apoptotic and pyroptotic cell death in the hippocampus as evidenced by increases of cleaved caspase 3 positive hippocampal neurons, TUNEL-positive cells, protein levels of p53, Bax, Puma, and the cleaved GSDMD N-terminal fragment, all of which were decreased in NLRP3 deficient mice. Streptozocin BCL2-associated X protein Mus musculus