Pub. Date : 2020 May
PMID : 32453744
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, we find increased expression of beta-site cleaving enzyme (BACE1), APP, and Abeta in human primary astrocytes (HPAs) exposed to Tat. | Triethylenemelamine | beta-secretase 1 | Homo sapiens |
| 2 | This is the first report implicating the role of the HIF-1alpha/lncRNABACE1-AS/BACE1 axis in Tat-mediated induction of astrocytic amyloidosis, which could be targeted as adjunctive therapies for HAND-associated Alzheimer-like comorbidity. | Triethylenemelamine | beta-secretase 1 | Homo sapiens |