Title : Human platelets express functional ectonucleotidases that restrict platelet activation signaling.

Pub. Date : 2020 Jun 18

PMID : 32446352






1 Functional Relationships(s)
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1 Interestingly, inhibition of CD73 in thrombin-treated platelets led to enhanced tyrosine phosphorylation of proteins and rise in intracellular free calcium, [Ca2+]i, thus signifying the inhibitory role of the ectonucleotidase on agonist-mediated platelet signaling. Tyrosine coagulation factor II, thrombin Homo sapiens