Title : Reduced expression of CYLD promotes cell survival and inflammation in gefitinib-treated NSCLC PC-9 cells: Targeting CYLD may be beneficial for acquired resistance to gefitinib therapy.

Pub. Date : 2020 Sep

PMID : 32441799






1 Functional Relationships(s)
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1 In addition, silencing the expression of CYLD resulted in increase of the expression level of IL-6, TGF-beta and TNF-alpha, which may contribute to acquired resistance of PC-9 cells to gefitinib. Gefitinib interleukin 6 Homo sapiens