Title : Acidosis-Induced TGF-β2 Production Promotes Lipid Droplet Formation in Dendritic Cells and Alters Their Potential to Support Anti-Mesothelioma T Cell Response.

Pub. Date : 2020 May 19

PMID : 32438640






2 Functional Relationships(s)
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1 Interestingly, inhibition of TGF-beta2 signaling and diacylglycerol O-acyltransferase (DGAT), the last enzyme involved in triglyceride synthesis, led to a significant restoration of DC activity and anticancer immune response. Triglycerides diacylglycerol O-acyltransferase 1 Homo sapiens
2 Interestingly, inhibition of TGF-beta2 signaling and diacylglycerol O-acyltransferase (DGAT), the last enzyme involved in triglyceride synthesis, led to a significant restoration of DC activity and anticancer immune response. Triglycerides diacylglycerol O-acyltransferase 1 Homo sapiens