Protein Name diacylglycerol O-acyltransferase 1
Organism Homo sapiens
Gene ID 8694
Gene Symbol

DGAT1

UniProt O75907 (DGAT1_HUMAN)
Relationships Total Number of functionally related compound(s) : 190
Total Number of Articles : 200
Description

diacylglycerol O-acyltransferase 1

Gene Summary

This gene encodes an multipass transmembrane protein that functions as a key metabolic enzyme. The encoded protein catalyzes the conversion of diacylglycerol and fatty acyl CoA to triacylglycerol. This enzyme can also transfer acyl CoA to retinol. Activity of this protein may be associated with obesity and other metabolic diseases. [provided by RefSeq, Jul 2013]

synonyms
  • diacylglycerol O-acyltransferase 1
  • ACAT related gene product 1
  • acyl coenzyme A:cholesterol acyltransferase related gene 1
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Properties