Pub. Date : 2020 Jul 17
PMID : 32433863
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cooperativity Between Orthosteric Inhibitors and Allosteric Inhibitor 8-Anilino-1-Naphthalene Sulfonic Acid (ANS) in Cyclin-Dependent Kinase 2. | 8-anilino-1-naphthalenesulfonic acid | cyclin dependent kinase 2 | Homo sapiens |
| 2 | Cooperativity Between Orthosteric Inhibitors and Allosteric Inhibitor 8-Anilino-1-Naphthalene Sulfonic Acid (ANS) in Cyclin-Dependent Kinase 2. | 8-anilino-1-naphthalenesulfonic acid | cyclin dependent kinase 2 | Homo sapiens |
| 3 | We have previously discovered that 8-anilino-1-naphthalene sulfonic acid (ANS) binds an allosteric pocket in cyclin-dependent kinase 2 (Cdk2). | 8-anilino-1-naphthalenesulfonic acid | cyclin dependent kinase 2 | Homo sapiens |
| 4 | We have previously discovered that 8-anilino-1-naphthalene sulfonic acid (ANS) binds an allosteric pocket in cyclin-dependent kinase 2 (Cdk2). | 8-anilino-1-naphthalenesulfonic acid | cyclin dependent kinase 2 | Homo sapiens |
| 5 | We have previously discovered that 8-anilino-1-naphthalene sulfonic acid (ANS) binds an allosteric pocket in cyclin-dependent kinase 2 (Cdk2). | 8-anilino-1-naphthalenesulfonic acid | cyclin dependent kinase 2 | Homo sapiens |
| 6 | We have previously discovered that 8-anilino-1-naphthalene sulfonic acid (ANS) binds an allosteric pocket in cyclin-dependent kinase 2 (Cdk2). | 8-anilino-1-naphthalenesulfonic acid | cyclin dependent kinase 2 | Homo sapiens |
| 7 | Here, we detail the positive cooperativity between ANS and orthosteric Cdk2 inhibitors dinaciclib and roscovitine, which increase the affinity of ANS toward Cdk2 5-fold to 10-fold, and the relatively noncooperative effects of ATP. | 8-anilino-1-naphthalenesulfonic acid | cyclin dependent kinase 2 | Homo sapiens |
| 8 | Here, we detail the positive cooperativity between ANS and orthosteric Cdk2 inhibitors dinaciclib and roscovitine, which increase the affinity of ANS toward Cdk2 5-fold to 10-fold, and the relatively noncooperative effects of ATP. | 8-anilino-1-naphthalenesulfonic acid | cyclin dependent kinase 2 | Homo sapiens |
| 9 | Here, we detail the positive cooperativity between ANS and orthosteric Cdk2 inhibitors dinaciclib and roscovitine, which increase the affinity of ANS toward Cdk2 5-fold to 10-fold, and the relatively noncooperative effects of ATP. | 8-anilino-1-naphthalenesulfonic acid | cyclin dependent kinase 2 | Homo sapiens |