Pub. Date : 2020 May
PMID : 32432758
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Prostaglandin E2 receptor subtypes 1 and 2 play a role in TGF-beta1-induced renal fibrosis by regulating endoplasmic reticulum stress. | Dinoprostone | transforming growth factor, beta 1 | Mus musculus |
| 2 | OBJECTIVE: This study aimed to investigate the effects of prostaglandin E2 receptor subtypes 1 (EP1) and 2 (EP2) on endoplasmic reticulum (ER) stress induced by TGF-beta1 in mouse mesangial cells (MCs) and to explore its potential mechanisms. | Dinoprostone | transforming growth factor, beta 1 | Mus musculus |
| 3 | RESULTS: TGF-beta1 induced mesangial cell proliferation and increased PGE2 secretion. | Dinoprostone | transforming growth factor, beta 1 | Mus musculus |