Title : The JAK2/STAT3 pathway is involved in dexmedetomidine-induced myocardial protection in rats undergoing cardiopulmonary bypass.

Pub. Date : 2020 Apr

PMID : 32395527






2 Functional Relationships(s)
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1 The JAK2/STAT3 pathway is involved in dexmedetomidine-induced myocardial protection in rats undergoing cardiopulmonary bypass. Dexmedetomidine Janus kinase 2 Rattus norvegicus
2 Moreover, qRT-PCR results revealed that dexmedetomidine administration reduced the expression of JAK2 and STAT3 mRNA (P<0.05); pJAK2 and pSTAT3 (P<0.05) protein levels were also reduced as assessed by western blotting and immunohistochemistry (P<0.05). Dexmedetomidine Janus kinase 2 Rattus norvegicus