Title : Enhanced genome editing in human iPSCs with CRISPR-CAS9 by co-targeting ATP1a1.

Pub. Date : 2020

PMID : 32391204






1 Functional Relationships(s)
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1 Collectively, these results suggest that a plasmid donor with a 400 bp repair template is an optimal donor DNA for targeted substitution and co-targeting ATP1A1 with the second locus enriches for mutagenesis events through cardiac glycoside selection in human iPSCs. Glycosides ATPase Na+/K+ transporting subunit alpha 1 Homo sapiens