Title : PTPROt aggravates inflammation by enhancing NF-κB activation in liver macrophages during nonalcoholic steatohepatitis.

Pub. Date : 2020

PMID : 32373213






1 Functional Relationships(s)
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1 Moreover, PTPROt promotes the transcription of pro-oxidant genes and inhibits antioxidant and protective genes via increased activation of the NF-kappaB signaling pathway, thereby causing an increased level of reactive oxygen species (ROS) and damaged mitochondria. Reactive Oxygen Species nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus