Title : Hyperoside attenuates pregnancy loss through activating autophagy and suppressing inflammation in a rat model.

Pub. Date : 2020 Aug 1

PMID : 32360572






2 Functional Relationships(s)
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1 In addition, hyperoside treatment downregulated the expressions of phosphorylated mammalian target of rapamycin (mTOR), phosphorylated p70S6 Kinase (S6K) and inhibited the expressions of Toll-like receptor 4 (TLR4), myeloid differentiation factor 88 (MyD88) and NF-kB p-p65 in pregnancy loss animal models. hyperoside ribosomal protein S6 kinase B1 Homo sapiens
2 SIGNIFICANCE: Hyperoside attenuated pregnancy loss through regulating mTOR/S6K and TLR4/MyD88/NF-kB signaling pathways, which may provide a potential drug candidate for recurrent pregnancy loss therapy. hyperoside ribosomal protein S6 kinase B1 Homo sapiens