Pub. Date : 2020 Jul
PMID : 32323562
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PKM2 Activator TEPP-46 Attenuates Thoracic Aortic Aneurysm and Dissection by Inhibiting NLRP3 Inflammasome-Mediated IL-1beta Secretion. | TEPP-46 | NLR family, pyrin domain containing 3 | Mus musculus |
| 2 | Furthermore, TEPP-46 treatment also suppressed the activation of the NOD-like receptor (NLR) family and pyrin domain-containing protein 3 (NLRP3) inflammasome by downregulating p-STAT3 and HIF1-alpha. | TEPP-46 | NLR family, pyrin domain containing 3 | Mus musculus |