Pub. Date : 2020 Jun
PMID : 32323054
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dexmedetomidine had neuroprotective effects on hippocampal neuronal cells via targeting lncRNA SHNG16 mediated microRNA-10b-5p/BDNF axis. | Dexmedetomidine | brain-derived neurotrophic factor | Rattus norvegicus |
| 2 | DEX inhibited miR-10b-5p expression but increased SHNG16 and BDNF levels with a dosage effect. | Dexmedetomidine | brain-derived neurotrophic factor | Rattus norvegicus |
| 3 | In conclusion, DEX exerts neuroprotective in ischemic stroke via improving neuron damage, the underlying mechanism may be upregulating SHNG16 and BDNF via sponging miR-10b-5p. | Dexmedetomidine | brain-derived neurotrophic factor | Rattus norvegicus |