Title : Impact of HLA-B*52:01-Driven Escape Mutations on Viral Replicative Capacity.

Pub. Date : 2020 Jun 16

PMID : 32321820






1 Functional Relationships(s)
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1 We here examined the impact of HLA-B*52:01-associated viral polymorphisms within the immunodominant C-clade Gag epitope RMTSPVSI ("RI8"; Gag residues 275-282) on viral replicative capacity (VRC), since HLA-mediated reduction in VRC is a central mechanism implicated in HLA-associated control of HIV. Glycosaminoglycans major histocompatibility complex, class I, B Homo sapiens