Pub. Date : 2020
PMID : 32317968
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Trichomicin Suppresses Colorectal Cancer via Comprehensive Regulation of IL-6 and TNFalpha in Tumor Cells, TAMs, and CAFs. | trichomicin | interleukin 6 | Mus musculus |
| 2 | The expression levels of IL-6 and TNFalpha were reduced in tumor tissues of mice treated with Trichomicin, which was consistent with results of in vitro experiments in which Trichomicin suppressed the expression of IL-6 and TNFalpha in tumor and stromal cells. | trichomicin | interleukin 6 | Mus musculus |
| 3 | The expression levels of IL-6 and TNFalpha were reduced in tumor tissues of mice treated with Trichomicin, which was consistent with results of in vitro experiments in which Trichomicin suppressed the expression of IL-6 and TNFalpha in tumor and stromal cells. | trichomicin | interleukin 6 | Mus musculus |
| 4 | The expression levels of IL-6 and TNFalpha were reduced in tumor tissues of mice treated with Trichomicin, which was consistent with results of in vitro experiments in which Trichomicin suppressed the expression of IL-6 and TNFalpha in tumor and stromal cells. | trichomicin | interleukin 6 | Mus musculus |
| 5 | The expression levels of IL-6 and TNFalpha were reduced in tumor tissues of mice treated with Trichomicin, which was consistent with results of in vitro experiments in which Trichomicin suppressed the expression of IL-6 and TNFalpha in tumor and stromal cells. | trichomicin | interleukin 6 | Mus musculus |
| 6 | Conclusively, Trichomicin, a promising new drug candidate with antitumor activity, exerted antitumor effects against colon cancer through inhibition of the IL-6 and TNFalpha signaling pathways. | trichomicin | interleukin 6 | Mus musculus |