Title : Spinal cord NLRP1 inflammasome contributes to dry skin induced chronic itch in mice.

Pub. Date : 2020 Apr 20

PMID : 32312281






1 Functional Relationships(s)
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1 RESULTS: AEW treatment triggers spontaneous scratching and significantly increases the expression of NLRP1, ASC, and caspase-1 and the levels of IL-1beta, IL-18, IL-6, and TNF-alpha in the spinal cord and the skin of mice. 1-(3-Amino-2-Methylbenzyl)-4-Hexylpyridin-2(1h)-One interleukin 6 Mus musculus