Title : Paeoniflorin suppresses IL-33 production by macrophages.

Pub. Date : 2020 Jun

PMID : 32312124






1 Functional Relationships(s)
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1 Notably, NF-kappaB inhibitor (BAY 11-7085), P38MAPK inhibitor (SB203580), and Ca2+ blocker (NiCl2) also curbed LPS-induced IL-33 production, respectively.Conclusions: PF suppresses IL-33 production by macrophages via inhibiting NF-kappaB and P38MAPK activation associated with the regulation of Ca2+ mobilization. BAY 11-7085 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus