Pub. Date : 2020
PMID : 32308720
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sesamin Promotes Neurite Outgrowth under Insufficient Nerve Growth Factor Condition in PC12 Cells through ERK1/2 Pathway and SIRT1 Modulation. | sesamin | nerve growth factor | Rattus norvegicus |
| 2 | In this study, the potentiating effect of sesamin, a major lignan in sesame seeds (Sesamum indicum) and oil, on NGF-induced neurogenesis and its involved mechanisms were firstly reported. | sesamin | nerve growth factor | Rattus norvegicus |
| 3 | The neuronal markers including synaptophysin and growth-associated protein-43 along with the synaptic connections were significantly increased in combination treatment between sesamin and NGF. | sesamin | nerve growth factor | Rattus norvegicus |
| 4 | Taken together, the potentiating effect of sesamin on NGF-induced neurogenesis in this finding could be used for alternative treatment in neurodegenerative diseases, including Alzheimer"s disease. | sesamin | nerve growth factor | Rattus norvegicus |