Title : A Population Pharmacokinetics Model for Vancomycin Dosage Optimization Based on Serum Cystatin C.

Pub. Date : 2020 Aug

PMID : 32304024






6 Functional Relationships(s)
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1 A Population Pharmacokinetics Model for Vancomycin Dosage Optimization Based on Serum Cystatin C. Vancomycin cystatin C Homo sapiens
2 BACKGROUND AND OBJECTIVES: Renal function has an important influence on the pharmacokinetics of vancomycin, and serum cystatin C (CysC) exhibits accurate predictive performance as a marker for renal function. Vancomycin cystatin C Homo sapiens
3 BACKGROUND AND OBJECTIVES: Renal function has an important influence on the pharmacokinetics of vancomycin, and serum cystatin C (CysC) exhibits accurate predictive performance as a marker for renal function. Vancomycin cystatin C Homo sapiens
4 This study aimed to develop a population pharmacokinetics (PopPK) model of vancomycin based on serum CysC in pediatric patients. Vancomycin cystatin C Homo sapiens
5 Serum CysC and age were significant covariates affecting the pharmacokinetics of vancomycin. Vancomycin cystatin C Homo sapiens
6 CONCLUSIONS: The pharmacokinetic parameters for vancomycin in pediatric patients were estimated using a serum CysC model. Vancomycin cystatin C Homo sapiens