Pub. Date : 2020 Aug
PMID : 32304024
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | A Population Pharmacokinetics Model for Vancomycin Dosage Optimization Based on Serum Cystatin C. | Vancomycin | cystatin C | Homo sapiens |
2 | BACKGROUND AND OBJECTIVES: Renal function has an important influence on the pharmacokinetics of vancomycin, and serum cystatin C (CysC) exhibits accurate predictive performance as a marker for renal function. | Vancomycin | cystatin C | Homo sapiens |
3 | BACKGROUND AND OBJECTIVES: Renal function has an important influence on the pharmacokinetics of vancomycin, and serum cystatin C (CysC) exhibits accurate predictive performance as a marker for renal function. | Vancomycin | cystatin C | Homo sapiens |
4 | This study aimed to develop a population pharmacokinetics (PopPK) model of vancomycin based on serum CysC in pediatric patients. | Vancomycin | cystatin C | Homo sapiens |
5 | Serum CysC and age were significant covariates affecting the pharmacokinetics of vancomycin. | Vancomycin | cystatin C | Homo sapiens |
6 | CONCLUSIONS: The pharmacokinetic parameters for vancomycin in pediatric patients were estimated using a serum CysC model. | Vancomycin | cystatin C | Homo sapiens |