PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32304024-0 2020 A Population Pharmacokinetics Model for Vancomycin Dosage Optimization Based on Serum Cystatin C. Vancomycin 40-50 cystatin C Homo sapiens 86-96 32304024-1 2020 BACKGROUND AND OBJECTIVES: Renal function has an important influence on the pharmacokinetics of vancomycin, and serum cystatin C (CysC) exhibits accurate predictive performance as a marker for renal function. Vancomycin 96-106 cystatin C Homo sapiens 118-128 32304024-1 2020 BACKGROUND AND OBJECTIVES: Renal function has an important influence on the pharmacokinetics of vancomycin, and serum cystatin C (CysC) exhibits accurate predictive performance as a marker for renal function. Vancomycin 96-106 cystatin C Homo sapiens 130-134 32304024-2 2020 This study aimed to develop a population pharmacokinetics (PopPK) model of vancomycin based on serum CysC in pediatric patients. Vancomycin 75-85 cystatin C Homo sapiens 101-105 32304024-7 2020 Serum CysC and age were significant covariates affecting the pharmacokinetics of vancomycin. Vancomycin 81-91 cystatin C Homo sapiens 6-10 32304024-10 2020 CONCLUSIONS: The pharmacokinetic parameters for vancomycin in pediatric patients were estimated using a serum CysC model. Vancomycin 48-58 cystatin C Homo sapiens 110-114