Pub. Date : 2020 Aug
PMID : 32302669
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, by using live cell imaging and biochemical approaches, we demonstrate that IFN-gamma plus high glucose augment endothelial connexin43 hemichannel activity, resulting in the increase of ATP release, ATP-mediated Ca2+ dynamics and production of nitric oxide and superoxide anion, as well as impaired insulin-mediated uptake and intercellular diffusion of glucose and cell survival. | Nitric Oxide | interferon gamma | Homo sapiens |