Title : The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway.

Pub. Date : 2020 Jun 15

PMID : 32284348






1 Functional Relationships(s)
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Protein Name
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1 In response to stress, an intricate molecular mechanism facilitated by sensor cysteines within KEAP1 allows NRF2 to escape ubiquitination, accumulate within the cell, and translocate to the nucleus, where it can promote its antioxidant transcription program. Cysteine NFE2 like bZIP transcription factor 2 Homo sapiens