Title : Anticancer activity of THMPP: Downregulation of PI3K/ S6K1 in breast cancer cell line.

Pub. Date : 2020 Apr

PMID : 32273810






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Gene expression analysis has shown that THMPP was able to downregulate the expression of PI3K/S6K1 genes, possibly via EGFR signaling pathway in both the cell lines, MCF-7 and SkBr3. thmpp epidermal growth factor receptor Homo sapiens
2 Further, molecular docking also confirms the potential binding of THMPP with EGFR. thmpp epidermal growth factor receptor Homo sapiens
3 Overall, the results suggest that THMPP induced cell death might be regulated by EGFR signaling pathway which augments THMPP being developed as a potential candidate for treating breast cancer. thmpp epidermal growth factor receptor Homo sapiens
4 Overall, the results suggest that THMPP induced cell death might be regulated by EGFR signaling pathway which augments THMPP being developed as a potential candidate for treating breast cancer. thmpp epidermal growth factor receptor Homo sapiens