Title : Lack of Correlation between In Vitro and In Vivo Studies on the Inhibitory Effects of (‒)-Sophoranone on CYP2C9 is Attributable to Low Oral Absorption and Extensive Plasma Protein Binding of (‒)-Sophoranone.

Pub. Date : 2020 Apr 7

PMID : 32272615






1 Functional Relationships(s)
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1 Additionally, it strongly inhibited other CYP2C9-catalyzed diclofenac 4"-hydroxylation and losartan oxidation activities. Diclofenac cytochrome P450 family 2 subfamily C member 9 Homo sapiens