Title : Highly efficient gene transfection by a hyperosmotic polymannitol based gene tranporter through regulation of caveolae and COX-2 induced endocytosis.

Pub. Date : 2014 May 14

PMID : 32261432






2 Functional Relationships(s)
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1 Cyclooxygenase-2 (COX-2) inhibition by SC58236 revealed the up-regulation of this osmoprotectant molecule against the hyperosmotic activity of polymannitol, inducing rapid endocytosis of PMGT in order to re-balance the hyperosmotic environment. osmoprotectant prostaglandin-endoperoxide synthase 2 Homo sapiens
2 Cyclooxygenase-2 (COX-2) inhibition by SC58236 revealed the up-regulation of this osmoprotectant molecule against the hyperosmotic activity of polymannitol, inducing rapid endocytosis of PMGT in order to re-balance the hyperosmotic environment. osmoprotectant prostaglandin-endoperoxide synthase 2 Homo sapiens