Title : Injectable colloidal hydrogel with mesoporous silica nanoparticles for sustained co-release of microRNA-222 and aspirin to achieve innervated bone regeneration in rat mandibular defects.

Pub. Date : 2019 Apr 28

PMID : 32255005






1 Functional Relationships(s)
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1 In a rat mandibular bone defect, injection of the co-delivered MSN hydrogel resulted in neurogenesis and enhanced bone formation, indicating that the present injectable miR222- and ASP-co-delivering colloidal hydrogel is a promising material for innervated bone tissue engineering. mannostatin A assembly factor for spindle microtubules Homo sapiens