Title : The differential mobilization of human neutrophil granules. Effects of phorbol myristate acetate and ionophore A23187.

Pub. Date : 1977 May

PMID : 322507






2 Functional Relationships(s)
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1 Phorbol myristate acetate (PMA, 2 to 100 ng/ml) and ionophore A23187 (10(-7) to 10(-6) M) cause human neutrophils to release up to 50% of the granule-associated enzyme lysozyme extracellularly without release of beta-glucuronidase or the cytoplasmic enzyme LDH. Tetradecanoylphorbol Acetate glucuronidase beta Homo sapiens
2 Phorbol myristate acetate (PMA, 2 to 100 ng/ml) and ionophore A23187 (10(-7) to 10(-6) M) cause human neutrophils to release up to 50% of the granule-associated enzyme lysozyme extracellularly without release of beta-glucuronidase or the cytoplasmic enzyme LDH. Tetradecanoylphorbol Acetate glucuronidase beta Homo sapiens