Title : JNK suppresses melanogenesis by interfering with CREB-regulated transcription coactivator 3-dependent MITF expression.

Pub. Date : 2020

PMID : 32226536






1 Functional Relationships(s)
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1 The selective JNK activator anisomycin also inhibited melanin production through phosphoinhibition of CRTC3, while JNK inhibition enhanced melanogenesis by stimulating CRTC3 dephosphorylation and nuclear migration. Anisomycin mitogen-activated protein kinase 8 Homo sapiens