Pub. Date : 2020
PMID : 32210794
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study, the mechanism of mercury chloride (HgCl2) induced inactivation of tyrosinase was investigated for the first time. | Mercuric Chloride | tyrosinase | Homo sapiens |
| 2 | A kinetic analysis revealed that HgCl2 inhibited tyrosinase activity in an irreversible non-competitive manner. | Mercuric Chloride | tyrosinase | Homo sapiens |
| 3 | The strong intrinsic fluorescence quenching suggested that the formation of the HgCl2-tyrosinase complex induced conformational changes of the enzyme, and HgCl2 had only one single binding site or a single class of binding site on tyrosinase. | Mercuric Chloride | tyrosinase | Homo sapiens |
| 4 | The strong intrinsic fluorescence quenching suggested that the formation of the HgCl2-tyrosinase complex induced conformational changes of the enzyme, and HgCl2 had only one single binding site or a single class of binding site on tyrosinase. | Mercuric Chloride | tyrosinase | Homo sapiens |
| 5 | The molecular docking and further experiments demonstrated that HgCl2 bound to the amino residuals (His) in the catalytic center of tyrosinase. | Mercuric Chloride | tyrosinase | Homo sapiens |