Pub. Date : 2020 Sep
PMID : 32209809
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here, we established that the alpha4beta2* nAChR agonist epibatidine can function as a discriminative stimulus in mice. | epibatidine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
2 | The partial alpha4beta2* nAChR agonists varenicline and 2"-fluoro-3"-(4-nitro-phenyl)deschloroepibatidine produced 61 and 69% epibatidine-appropriate responding, respectively. | epibatidine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
3 | These results show that epibatidine may be trained as a discriminative stimulus in mice and has utility in elucidating the in-vivo pharmacology of alpha4beta2* nAChR ligands. | epibatidine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |