Title : Metformin inhibits high glucose-induced smooth muscle cell proliferation and migration.

Pub. Date : 2020 Mar 24

PMID : 32208365






4 Functional Relationships(s)
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1 Correlations between metformin concentration and high-mobility group box 1 (HMGB1) and miR-142-3p levels were assessed. Metformin high mobility group box 1 Homo sapiens
2 HMGB1 gene expression correlated negatively with metformin concentration, whereas miR-142-3p expression correlated positively with metformin concentration. Metformin high mobility group box 1 Homo sapiens
3 Metformin inhibits high glucose-induced VSMC hyperproliferation and increased migration by inducing miR-142-3p-mediated inhibition of HMGB1 expression via the HMGB1-autophagy related pathway. Metformin high mobility group box 1 Homo sapiens
4 Metformin inhibits high glucose-induced VSMC hyperproliferation and increased migration by inducing miR-142-3p-mediated inhibition of HMGB1 expression via the HMGB1-autophagy related pathway. Metformin high mobility group box 1 Homo sapiens