Title : circ_0000638 inhibits neodymium oxide-induced bronchial epithelial cell inflammation through the miR-498-5p/NF-κB axis.

Pub. Date : 2020 Jun 1

PMID : 32199215






2 Functional Relationships(s)
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1 Moreover, circ_0000638 reduced the expression of IL-8 and IL-1beta by inhibiting NF-kappaB activation in neodymium oxide-treated 16HBE cells. 16hbe nuclear factor kappa B subunit 1 Homo sapiens
2 These results suggest that circ_0000638 can inhibit NF-kappaB activation by competitively binding to miR-498-5p, further downregulating the expression of IL-8 and IL-1beta in neodymium oxide-treated 16HBE cells. 16hbe nuclear factor kappa B subunit 1 Homo sapiens