Title : Only IL-1β release is inflammasome-dependent upon ultraviolet B irradiation although IL-18 is also secreted.

Pub. Date : 2020 May

PMID : 32190930






2 Functional Relationships(s)
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1 At the mechanistic level, the release of IL-1beta was regulated by K+ efflux, whereas the secretion of IL-18 was dependent on ROS production. Reactive Oxygen Species interleukin 18 Homo sapiens
2 Collectively, our data suggest that UVB clearly stimulates the secretion of mature IL-18 as a result of ROS induction, and this response is associated with DNA damage. Reactive Oxygen Species interleukin 18 Homo sapiens