Pub. Date : 2020 Mar 14
PMID : 32183350
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Maternal Fat-1 Transgene Protects Offspring from Excess Weight Gain, Oxidative Stress, and Reduced Fatty Acid Oxidation in Response to High-Fat Diet. | Fatty Acids | FAT atypical cadherin 1 | Homo sapiens |
| 2 | Here, we tested whether dams expressing the fat-1 transgene, which endogenously converts omega-6 (n-6) to omega-3 (n-3) polyunsaturated fatty acid, could protect wild-type (WT) offspring against high-fat diet induced weight gain, oxidative stress, and disrupted mitochondrial fatty acid oxidation. | Fatty Acids | FAT atypical cadherin 1 | Homo sapiens |
| 3 | In particular, WT males from fat-1 high-fat-fed dams were protected from post-weaning high-fat diet induced weight gain, reduced fatty acid oxidation, or excess oxidative stress compared with offspring of WT high-fat-fed dams. | Fatty Acids | FAT atypical cadherin 1 | Homo sapiens |
| 4 | Fat-1 offspring were protected from the reduced fatty acid oxidation and excess oxidative stress observed in offspring of WT high-fat-fed dams. | Fatty Acids | FAT atypical cadherin 1 | Homo sapiens |