Title : Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure.

Pub. Date : 2020 Apr

PMID : 32180563






1 Functional Relationships(s)
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1 METHODS: Here we report that the oxidoreductase cytochrome b5 reductase 3 (Cyb5r3) links FoxO1 signaling to beta-cell stimulus/secretion coupling by regulating mitochondrial function, reactive oxygen species generation, and nicotinamide actin dysfunction (NAD)/reduced nicotinamide actin dysfunction (NADH) ratios. nadide forkhead box O1 Mus musculus