Title : Phosphoproteomics identifies a bimodal EPHA2 receptor switch that promotes embryonic stem cell differentiation.

Pub. Date : 2020 Mar 13

PMID : 32170114






1 Functional Relationships(s)
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1 Mechanistically, FGF4-ERK1/2-RSK signalling inhibits EPHA2 via Ser/Thr phosphorylation, whilst FGF4-ERK1/2 disrupts a core pluripotency transcriptional circuit required for Epha2 gene expression. Serine EPH receptor A2 Homo sapiens