Title : Treating Autoimmune Diseases by Targeting IL-23 with Gene-Silencing Pyrrole-Imidazole Polyamide.

Pub. Date : 2020 Apr 15

PMID : 32169850






2 Functional Relationships(s)
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1 To develop a novel gene-silencing agent that targets IL-23/IL-17 axis, we designed polyamide that specifically binds to the transcription factor c-Rel-binding site located in the promoter of IL-23p19 subunit. Nylons interleukin 23 subunit alpha Homo sapiens
2 To develop a novel gene-silencing agent that targets IL-23/IL-17 axis, we designed polyamide that specifically binds to the transcription factor c-Rel-binding site located in the promoter of IL-23p19 subunit. Nylons interleukin 23 subunit alpha Homo sapiens