Protein Name interleukin 23 subunit alpha
Organism Homo sapiens
Gene ID 51561
Gene Symbol


UniProt Q9NPF7 (IL23A_HUMAN)
Relationships Total Number of functionally related compound(s) : 418
Total Number of Articles : 520

interleukin 23 subunit alpha

Gene Summary

This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq, Jul 2008]

  • interleukin-23 subunit alpha
  • IL-23 subunit alpha
  • IL-23-A
Click to show/hide the synonyms