Pub. Date : 2020 May
PMID : 32167393
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Idasanutlin is a small-molecule inhibitor of MDM2, a negative regulator of tumor suppressor p53. | RG7388 | MDM2 proto-oncogene | Homo sapiens |
| 2 | By preventing the p53-MDM2 interaction, idasanutlin allows for p53 activation, particularly in patients with TP53 wild-type (WT) status. | RG7388 | MDM2 proto-oncogene | Homo sapiens |