Title : Cytochrome P450 Enzyme-Mediated Bioactivation as an Underlying Mechanism of Columbin-Induced Hepatotoxicity.

Pub. Date : 2020 Apr 20

PMID : 32162908






1 Functional Relationships(s)
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1 The present study demonstrated that columbin was hepatotoxic and CYP3A4-mediated bioactivation of the furan ring would serve as an underlying mechanism for columbin-induced hepatotoxicity. furan cytochrome P450 family 3 subfamily A member 4 Homo sapiens