Pub. Date : 2020 Mar 11
PMID : 32161285
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cellular cholesterol is mainly regulated at the transcriptional level by SREBP2, but also through uptake of extracellular cholesterol from low density lipoproteins (LDL) via expression of LDL receptors (LDLR) at the cell surface. | Cholesterol | sterol regulatory element binding transcription factor 2 | Homo sapiens |
| 2 | We show that NBEAL1 regulates cholesterol metabolism by modulating LDLR expression in a mechanism involving interaction with SCAP and PAQR3 and subsequent SREBP2-processing. | Cholesterol | sterol regulatory element binding transcription factor 2 | Homo sapiens |