Title : Curcumin augments therapeutic efficacy of TRAIL-based immunotoxins in leukemia.

Pub. Date : 2020 Aug

PMID : 32141025






1 Functional Relationships(s)
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1 RESULTS: Curcumin augments TRAIL-apoptotic signaling in leukemic cells by upregulating the expression of DR4 and DR5 along with suppression of cFLIP and anti-apoptotic proteins Mcl-1, Bcl-xl, and XIAP. Curcumin MCL1 apoptosis regulator, BCL2 family member Homo sapiens