Title : Evidence that TNF-β suppresses osteoblast differentiation of mesenchymal stem cells and resveratrol reverses it through modulation of NF-κB, Sirt1 and Runx2.

Pub. Date : 2020 Jul

PMID : 32140928






2 Functional Relationships(s)
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1 Evidence that TNF-beta suppresses osteoblast differentiation of mesenchymal stem cells and resveratrol reverses it through modulation of NF-kappaB, Sirt1 and Runx2. Resveratrol nuclear factor kappa B subunit 1 Homo sapiens
2 Finally, resveratrol was able to manifest its effect both by suppression of TNF-beta-induced NF-kappaB and through direct activation of the Sirt1 and Runx2 pathway. Resveratrol nuclear factor kappa B subunit 1 Homo sapiens