Title : Design and synthesis of a novel class EGFR/HER2 dual inhibitors containing tricyclic oxazine fused quinazolines scaffold.

Pub. Date : 2020 May 1

PMID : 32139324






1 Functional Relationships(s)
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Protein Name
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1 Compounds 1e and 1h were identified as lead compounds which displayed almost 3-4 times more potent inhibition of EGFR and HER2 than the approved drug lapatinib. Hydrogen epidermal growth factor receptor Homo sapiens