Pub. Date : 2019 Dec
PMID : 32133068
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Silymarin ameliorated the histopathological lung injury with further up-regulation of Nrf-2 and HO-1 mRNA and decreased the inflammatory and fibrotic parameters together with up-regulation of the anti-apoptotic and the proliferation parameters. | Silymarin | NFE2 like bZIP transcription factor 2 | Rattus norvegicus |
| 2 | Conclusion: The protective effect of silymarin against ALI is mediated by Nrf-2/HO-1 pathway with subsequent antioxidant, anti-inflammatory, antiapoptotic, and proliferating activities. | Silymarin | NFE2 like bZIP transcription factor 2 | Rattus norvegicus |