Pub. Date : 2020 May 21
PMID : 32128578
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Factor VIII exhibits chaperone-dependent and glucose-regulated reversible amyloid formation in the endoplasmic reticulum. | Glucose | coagulation factor VIII | Homo sapiens |
| 2 | We show that FVIII forms amyloid-like fibrils within the ER lumen upon increased FVIII synthesis or inhibition of glucose metabolism. | Glucose | coagulation factor VIII | Homo sapiens |
| 3 | Significantly, FVIII amyloids can be dissolved upon restoration of glucose metabolism to produce functional secreted FVIII. | Glucose | coagulation factor VIII | Homo sapiens |
| 4 | Significantly, FVIII amyloids can be dissolved upon restoration of glucose metabolism to produce functional secreted FVIII. | Glucose | coagulation factor VIII | Homo sapiens |