Title : [Evaluation of the Oral Absorption of Ester-type Prodrugs].

Pub. Date : 2020

PMID : 32115554






2 Functional Relationships(s)
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1 In the present study, we designed a prodrug of fexofenadine (FXD) as a model parent drug that is resistant to hCE2 but hydrolyzed by hCE1, utilizing the differences in catalytic characteristics of hCE1 and hCE2. fexofenadine carboxylesterase 2 Homo sapiens
2 In the present study, we designed a prodrug of fexofenadine (FXD) as a model parent drug that is resistant to hCE2 but hydrolyzed by hCE1, utilizing the differences in catalytic characteristics of hCE1 and hCE2. fexofenadine carboxylesterase 2 Homo sapiens